Aging-Well: Remote Monitoring for Adults at Risk for Alzheimer's Disease

What Is This Study About?

This observational study will use sensors in the home environment to capture changes in routine daily activities that may signal cognitive or functional decline in older adults with and without mild cognitive impairment. Participants will have a technology platform installed in their home environment for up to four years. The platform is designed to detect changes in daily activities, such as taking medications, using the computer, and driving, that could signal cognitive changes. It will include an electronic pillbox, software installed on the participants' home computer/laptop/tablet, and wireless sensors placed in their car. Participants will also complete baseline and annual study assessments and tests, as well as weekly and monthly online surveys. Researchers are investigating the approaches used in this study to help identify and monitor increasing risks for worsening cognitive function.

Do I Qualify To Participate in This Study?

Must have:

• Taking at least one medication daily
• Living within 15 miles of study site
• Vision and hearing corrected to normal

Must NOT have:

• Neurodegenerative diseases or dementias, including Alzheimer's, Parkinson's, Huntington's, vascular dementia, Lewy body dementia, and frontotemporal dementia
• Major neurological disorders (e.g., seizures/epilepsy, stroke or mini-stroke, multiple sclerosis, brain tumor, normal pressure hydrocephalus, brain infection, amyotrophic lateral sclerosis)
• History of significant brain injuries (e.g., loss of consciousness greater than 10 minutes, permanent brain lesion, anoxic/hypoxic encephalopathy)
• Major or uncontrolled/unstable physical condition or illness, inculding chronic kidney disease, uncontrolled diabetes, uncontrolled heart disease, uncontrolled chronic obstructive pulmonary disease, and cancer (unless removed/targeted through radiation)
• History of major psychiatric disorders, including schizophrenia, schizoaffective disorder, bipolar disorder, obsessive-compulsive disorder, or post-traumatic stress disorder
• Significant neurodevelopmental disorders, such as autism spectrum disorders, attention-deficit/hyperactivity disorder, or intellectual disability
• Substance use disorder diagnosis or treatment within last year
• Impaired cognition
• Loss of use of hands or very limited mobility
• Exposure to Agent Orange if showing symptoms
• Chemotherapy

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

 

Where Is This Study Located?

Minnesota
The University of Minnesota and Minneapolis VA Health Care System Minneapolis, MN 55417 Recruiting Adreanne Rivera 310-794-0213 adreannerivera@mednet.ucla.edu
Oregon
Oregon Health & Science University Portland, OR 97239 Recruiting Adreanne Rivera 310-794-0213 adreannerivera@mednet.ucla.edu