Start: June 2009
End: March 30, 2017
The removal of cataracts can improve vision and reduce accidents and falls. However, some individuals, caregivers, and primary care doctors are reluctant to proceed with cataract surgery once an individual is diagnosed with Alzheimer's disease because they think that cataract surgery will not improve the person's quality of life, vision, and cognition. The investigators have designed this study to determine whether or not this belief is true.
Minimum Age: 50 Years
Maximum Age: 90 Years
++Clinical diagnosis of possible/probable mild to moderate Alzheimer's disease (MMSE scores: 14-26 inclusive)++Bilateral visually significant cataracts++Best corrected visual acuity of 20/50 or worse in better eye++Community dwelling (including assisted living)++If taking psychotropic drug, must be with stable dosage for 30 days
++History of cataract removal; ocular pathology; or visually significant retinal or optic nerve abnormalities++Resides in a long-term nursing care facility++No desire for cataract surgery++Evidence of unstable cardiac or pulmonary function++History of uncontrolled diabetes, hypertension, congestive heart failure, angina, stroke in areas known to affect cognition, or renal failure++Life expectancy of less than 1 year++Down's syndrome
Contact study personnel listed either under the general study contact or the location nearest you.
Lead: University Hospitals Case Medical Center
Source: ClinicalTrials.gov ID: NCT00921297