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Cataract Removal and Alzheimer's Disease

Start: June 2009
End: March 30, 2017
Enrollment: 210

What Is This Study About?

The removal of cataracts can improve vision and reduce accidents and falls. However, some individuals, caregivers, and primary care doctors are reluctant to proceed with cataract surgery once an individual is diagnosed with Alzheimer's disease because they think that cataract surgery will not improve the person's quality of life, vision, and cognition. The investigators have designed this study to determine whether or not this belief is true.

Do I Qualify To Participate in This Study?

Minimum Age: 50 Years

Maximum Age: 90 Years

Must have:

++Clinical diagnosis of possible/probable mild to moderate Alzheimer's disease (MMSE scores: 14-26 inclusive)++Bilateral visually significant cataracts++Best corrected visual acuity of 20/50 or worse in better eye++Community dwelling (including assisted living)++If taking psychotropic drug, must be with stable dosage for 30 days

Must NOT have:

++History of cataract removal; ocular pathology; or visually significant retinal or optic nerve abnormalities++Resides in a long-term nursing care facility++No desire for cataract surgery++Evidence of unstable cardiac or pulmonary function++History of uncontrolled diabetes, hypertension, congestive heart failure, angina, stroke in areas known to affect cognition, or renal failure++Life expectancy of less than 1 year++Down's syndrome

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.


Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: University Hospitals Case Medical Center

Collaborator Sponsor

  • Case Western Reserve University
  • MetroHealth Medical Center
  • National Institutes of Health (NIH)

Source: ID: NCT00921297