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Cognitive and Aerobic Resilience for the Brain (CARB)

Start: January 2015
End: October 25, 2019
Enrollment: 200

What Is This Study About?

This trial will test the impact of cognitive and/or exercise training on cognition in older adults with mild cognitive impairment (MCI).

Do I Qualify To Participate in This Study?

Minimum Age: 65 Years

Maximum Age: N/A

Must have:

  • Subjective memory complaint
  • Minimal impairment in daily function per Functional Activity Questionnaire
  • Sedentary
  • English speaking
  • Access to telephone

Must NOT have:

  • Alzheimer's disease or another type of dementia
  • Stroke in the past 12 months
  • Myocardial infarction in the past 12 months
  • Angina
  • Parkinson's disease
  • Multiple sclerosis
  • Epilepsy
  • AIDS
  • Brain tumor, infection, or surgery; brain injury with loss of consciousness for more than 30 minutes
  • Schizophrenia or bipolar disorder
  • Cancer with short life expectancy; current chemotherapy or radiation therapy
  • Depression
  • Alcohol consumption of eight or more drinks per week for women, or 15 or more drinks per week for men
  • Prescription of Aricept or Namenda, past or present
  • Self-reported difficulty reading a newspaper (low visual acuity); low hearing or communication ability that would interfere with the study
  • Past involvement in similar cognitive training studies, programs, or online training
  • Past involvement in online brain training or brain fitness programs
  • Unable to pass the Exercise Assessment and Screening for You (EASY)
  • Living in nursing home
  • Unwilling to use a computer or be on videoconferencing
  • Baseline systolic blood pressure of >180, diastolic blood pressure of >100; baseline pulse of <40 or >100

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.


Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: Indiana University

Collaborator Sponsor

  • National Institute on Aging (NIA)

Source: ID: NCT02390453