Computer-Based Cognition Test To Detect Early-Stage Alzheimer's Disease

What Is This Study About?

Researchers have found that more people with mild cognitive impairment (MCI) than those without it go on to develop Alzheimer's disease or a related dementia. This study will evaluate whether the computer-based Cognitive Stress Test can effectively detect early-stage MCI to help identify people at risk for developing Alzheimer's disease. All participants will take computer-based and traditional cognition tests, and receive PET and MRI brain scans. Researchers will compare the cognitive function test results with the physical signs associated with Alzheimer's disease, including the amounts of abnormal tau and amyloid proteins in the brain and the size and thickness of certain brain regions.

Do I Qualify To Participate in This Study?

Must have:

• Participants must have either:
  • Mild cognitive impairment with:
    • Memory problems, as confirmed by a person who knows the participant well
    • No impairment in social or occupational functions
    • No evidence of a major neurocognitive disorder
  • Normal cognition with no memory problems, as confirmed by a person who knows the participant well
• Speak English or Spanish as their primary language

Must NOT have:

• Significant sensory or movement problems (e.g., visual or hearing impairment, paralysis)
• Diagnosis of a serious psychological disorder (e.g., major depression, bipolar disorder, psychotic disorder, substance use disorder)

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

 

Where Is This Study Located?

Florida
University of Miami, Center for Cognitive Neuroscience and Aging Miami, FL 33136 Recruiting Martin Orkuma 305-355-9060 mto9@miami.edu

Who Sponsors This Study?

Lead: University of Miami

Collaborator Sponsor

• National Institute on Aging