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Find more clinical trials

Curcumin and Yoga Therapy for Mild Cognitive Impairment

Start: January 2014
End: December 2020
Enrollment: 80

What Is This Study About?

This study will determine the impact of two interventions in people with early memory problems. First, it will test the clinical benefits of curcumin, a compound isolated from turmeric root, a component of Indian curry spices that has been found to inhibit several potential pathways in Alzheimer's disease. Second, it will determine the effect of adding a yoga-based physical exercise program.

Do I Qualify To Participate in This Study?

Minimum Age: 50 Years

Maximum Age: 90 Years

Must have:

  • Subjective cognitive complaints
  • Mini-Mental Status Exam (MMSE) score of 24; performance 1.5 standard deviation below average on Consortium to Establish a Registry for Alzheimer's Disease (CERAD) word list learning test
  • Essentially intact activities of daily living
  • Sedentary (exercise less than 30 minutes a day, 3 times a week)
  • Ambulatory
  • Able to exercise safely without cardiovascular symptoms and pass a graded treadmill test modified for the elderly
  • Community dwelling
  • Fluent in written and spoken English

Must NOT have:

  • Diagnosis of dementia
  • Concurrent substance abuse disorder, psychosis, or mood disorder
  • Neurological disease affecting motor or cognitive abilities (such as Parkinson's disease) or other significant uncontrolled medical problems
  • Initiation of any new medication/treatment for cognitive impairment (such as cholinesterase inhibitor or memantine) less than 6 months prior to study enrollment

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.


Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: VA Office of Research and Development

Source: ID: NCT01811381

An official website of the U.S. government, managed by the National Institutes on Aging at the National Institutes of Health