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Find more clinical trials

Down Syndrome Clinical Trials Network-Study of Alzheimer's Disease

Start: June 30, 2019
End: December 2023
Enrollment: 270

What Is This Study About?

Adults with Down syndrome are at increased risk for Alzheimer's disease as they age. The Longitudinal Investigation for the Enhancement of Down Syndrome Research (LIFE-DSR) is an observational study to understand the cognitive and behavioral changes and health issues in adults with Down syndrome as they progress toward Alzheimer's disease. Over two years, the researchers will assess changes in cognition, behavior, function, and health in people with Down syndrome. Blood will also be collected to find biomarkers that could help diagnose and track disease progression.

Do I Qualify To Participate in This Study?

Minimum Age: 25 Years

Maximum Age: N/A

Must have:

  • Diagnosis of Down syndrome
  • Study partner who has regular interaction, can participate in annual clinic visits, and can respond to questions about the participant
  • Participant and study partner must be capable of reliably completing study assessments

Must NOT have:

  • Participants and study partners who are not able to complete trial procedures or adhere to the schedule of study assessments

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.


Who Is the General Study Contact?

For more information about this study or study sites, visit About LIFE-DSR.

Study Contact
Angela L Britton, MA
Administrator LuMind IDSC

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Barrow Neurological Institute
Phoenix, AZ 85013
Sandy Quintanilla
University California Irvine
Irvine, CA 92697
Kelly Kilday
University of California, San Diego
La Jolla, CA 92093
Emily Little
Emory University
Atlanta, GA 30322
Helen Smith
Rush University Medical Center
Chicago, IL 60612
Melissa Baer
Advocate Health
Park Ridge, IL 60068
Monika Kapinos
Kansas University Medical Center
Fairway, KS 66205
Kayla Meyer
University Of Kentucky
Lexington, KY 40536
Roberta Davis
Kennedy Krieger Institute
Baltimore, MD 21205
Naomi Franklin
Massachusetts General Hospital
Boston, MA 02114
Ashlee Campbell
Massachusetts General Hospital
Charlestown, MA 02129
Kelsey Shelofsky
North Carolina
Duke University Medical Center
Durham, NC 27710
Gretchen Nichting
Cincinnatti Children's Hospital Medical Center
Cincinnati, OH 45229
Kellie Voth
Case Western Reserve University
Cleveland, OH 044106
Melissa Stasko

Who Sponsors This Study?

Lead: LuMind IDSC Foundation

Collaborator Sponsor

  • Alzheimer's Disease Cooperative Study (ADCS)

Source: ID: NCT04149197

An official website of the U.S. government, managed by the National Institutes on Aging at the National Institutes of Health