Down Syndrome Clinical Trials Network-Study of Alzheimer's Disease
Start: June 30, 2019
End: December 30, 2023
Enrollment: 270
What Is This Study About?
Adults with Down syndrome are at increased risk for Alzheimer's disease as they age. The Longitudinal Investigation for the Enhancement of Down Syndrome Research (LIFE-DSR) is an observational study to understand the cognitive and behavioral changes and health issues in adults with Down syndrome as they progress toward Alzheimer's disease. Over two years, the researchers will assess changes in cognition, behavior, function, and health in people with Down syndrome. Blood will also be collected to find biomarkers that could help diagnose and track disease progression.
Do I Qualify To Participate in This Study?
Minimum Age: 25 Years
Maximum Age: N/A
Must have:
- Diagnosis of Down syndrome
- Study partner who has regular interaction, can participate in annual clinic visits, and can respond to questions about the participant
- Participant and study partner must be capable of reliably completing study assessments
Must NOT have:
- Participants and study partners who are not able to complete trial procedures or adhere to the schedule of study assessments
If I Qualify, Who Do I Contact?
Contact study personnel listed either under the general study contact or the location nearest you.
Who Is the General Study Contact?
For more information about this study or study sites, visit About LIFE-DSR.
Need Help?
Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.
Where Is This Study Located?
| Arizona | |
|---|---|
|
Barrow Neurological Institute
Phoenix, AZ 85013
Recruiting
Sandy Quintanilla |
|
| California | |
|
University California Irvine
Irvine, CA 92697
Recruiting
Kelly Kilday |
|
|
University of California, San Diego
La Jolla, CA 92093
Recruiting
Emily Little |
|
| Georgia | |
|
Emory University
Atlanta, GA 30322
Recruiting
Helen Smith |
|
| Illinois | |
|
Rush University Medical Center
Chicago, IL 60612
Recruiting
Melissa Baer |
|
|
Advocate Health
Park Ridge, IL 60068
Recruiting
Monika Kapinos |
|
| Kansas | |
|
Kansas University Medical Center
Fairway, KS 66205
Recruiting
Kayla Meyer |
|
| Kentucky | |
|
University Of Kentucky
Lexington, KY 40536
Recruiting
Roberta Davis |
|
| Maryland | |
|
Kennedy Krieger Institute
Baltimore, MD 21205
Recruiting
Naomi Franklin |
|
| Massachusetts | |
|
Massachusetts General Hospital
Boston, MA 02114
Recruiting
Ashlee Campbell |
|
|
Massachusetts General Hospital
Charlestown, MA 02129
Recruiting
Kelsey Shelofsky |
|
| North Carolina | |
|
Duke University Medical Center
Durham, NC 27710
Recruiting
Gretchen Nichting |
|
| Ohio | |
|
Cincinnatti Children's Hospital Medical Center
Cincinnati, OH 45229
Recruiting
Kellie Voth |
|
|
Case Western Reserve University
Cleveland, OH 044106
Recruiting
Melissa Stasko |
|
Who Sponsors This Study?
Lead: LuMind IDSC Foundation
Collaborator Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Source: ClinicalTrials.gov ID: NCT04149197