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Find more clinical trials

Metal Endoprosthesis and Cognition

Start: March 12, 2021
End: September 2024
Enrollment: 150

What Is This Study About?

An endoprosthesis is an artificial device, often containing metal, placed inside the body to replace a missing body part. This study will explore whether people with an endoprosthesis due to bone cancer experience memory, thinking, or heart problems. Participants will complete an interview and questionnaires about their cognition. A close friend, spouse, or relative will also be interviewed about the participant's day-to-day cognition. Participants will provide blood samples and have echocardiograms at the start of the study, and after one and two years. Researchers will assess any changes in participant cognition, heart health, and the concentration of metals (cobalt, chromium, and titanium) in the blood over time.

Do I Qualify To Participate in This Study?

Minimum Age: 18 Years

Maximum Age: 100 Years

Must have:

  • Had surgery to implant an endoprosthesis following bone cancer
  • Participants may have memory problems, cognitive impairment, or no cognitive impairment

 

Must NOT have:

  • Current fracture or infection around the endoprosthesis
  • Pregnancy

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Study Contact
Peter C Brennan

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Minnesota
Mayo Clinic
Rochester, MN 55905
Recruiting
Peter C Brennan

Who Sponsors This Study?

Lead: Mayo Clinic

Collaborator Sponsor

  • National Institutes of Health (NIH)
  • National Heart, Lung, and Blood Institute (NHLBI)
  • National Institute on Aging (NIA)

Source: ClinicalTrials.gov ID: NCT04755140

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