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Genetic Characterization of Familial Dementia

Start: June 1, 2007
End: November 1, 2025
Enrollment: 20000

What Is This Study About?

In some families, Alzheimer's disease may be passed from generation to generation. This is called familial Alzheimer's disease. This study will identify genetic patterns in families affected by mild cognitive impairment, Alzheimer's disease, or a related dementia as compared to healthy individuals. All participants will provide a blood sample to allow researchers to sequence their DNA. The data collected will be stored in secure databases and, when shared for analysis, will not include any personally identifiable information that could be linked back to the donor.

Do I Qualify To Participate in This Study?

Minimum Age: 18 Years

Maximum Age: N/A

Must have:

  • Individuals with mild cognitive impairment, Alzheimer's disease, or a related dementia and/or their family members
  • Healthy individuals with no cognitive impairment or family history of dementia

Must NOT have:

  • Another neurological disease or condition that may interfere with the study, such as amyotrophic lateral sclerosis, frontotemporal lobar degeneration, multiple system atrophy, corticobasal degeneration, progressive supranuclear palsy, Huntington's disease, traumatic brain injury, drug or alcohol abuse, or schizophrenia (does not apply to family members)

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Study Contact
Michael Prough

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

University of Miami
Miami, FL 33136
Michael Prough

Who Sponsors This Study?

Lead: University of Miami

Collaborator Sponsor

  • Case Western Reserve University
  • Columbia University
  • Wake Forest University
  • National Institute on Aging (NIA)

Source: ID: NCT04680013