Start: April 1, 2021
End: May 2027
Diseases that impact blood vessels, such as high blood pressure and type 2 diabetes, are associated with the risk of dementia. This study will evaluate whether measuring hydrogen sulfide, a biomarker of blood vessel damage, can be used to detect blood vessel changes in the brain associated with dementia. Participants with cognitive impairment due to Alzheimer's disease or related dementia, and participants with no cognitive impairment will provide blood samples and undergo MRI brain scans. Researchers will measure hydrogen sulfide levels and changes in brain volume. In addition, because previous studies suggest that dementia risk varies by race and gender, study outcomes will be compared across these groups as well.
Minimum Age: 55 Years
Maximum Age: 100 Years
Contact study personnel listed either under the general study contact or the location nearest you.
LSU Health Shreveport Center for Brain Health
Shreveport, LA 71103
RecruitingElizabeth A Disbrow, PhD
Lead: Louisiana State University Health Sciences Center Shreveport
Source: ClinicalTrials.gov ID: NCT05060848