Start: June 17, 2021
End: December 2023
This study will investigate the effect of insulin, by nasal spray, on food intake and Alzheimer's disease risk factors, such as obesity, in African Americans. Participants will be randomly assigned to receive either insulin or a placebo by nasal spray before eating a prepared meal. All participants will also provide blood samples to test for APOE, a gene associated with Alzheimer's disease risk. The study involves four visits to the clinic with three provided lunches and some take-home meals. Researchers will measure food intake, hunger, memory and concentration, bone density, muscle, and body fat.
Minimum Age: 45 Years
Maximum Age: 65 Years
Contact study personnel listed either under the general study contact or the location nearest you.
Who Is the General Study Contact?
For more information and to enroll, visit the FIINAAL study website.
Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.
Lead: Pennington Biomedical Research Center
Source: ClinicalTrials.gov ID: NCT04739371