Start: December 6, 2021
End: October 31, 2022
Gamma waves are brain waves associated with focus and problem-solving. This study will test whether a device that delivers specific levels of light and sound to stimulate the brain can be used safely to increase brain gamma waves in people with Down syndrome. Down syndrome is characterized by an extra copy of chromosome 21, which increases the risk of Alzheimer's disease. Participants with and without Down syndrome will be randomly assigned to receive either gamma wave stimulation or a sham stimulation. Before and after brain stimulation, participants will complete cognitive testing to measure any changes in memory and cognitive performance and receive scans to measure any changes in brain wave activity. Throughout the study, all participants will be monitored for safety and tolerability. Future studies will address whether this type of intervention could be used to delay or treat Alzheimer's disease in people with Down syndrome.
Minimum Age: 25 Years
Maximum Age: 65 Years
Contact study personnel listed either under the general study contact or the location nearest you.
Massachusetts Institute of Technology
Cambridge, MA 02139
RecruitingGabrielle C de Weck, BS
Lead: Massachusetts Institute of Technology
Source: ClinicalTrials.gov ID: NCT05196984