Start: May 1, 2021
End: June 30, 2026
Different variants of the apolipoprotein E (APOE) gene have been associated with different levels of risk for developing Alzheimer's disease. This long-term study will gather data in cognitively normal older adults and compare cognitive, behavioral, and physical changes across different APOE variants, or genotypes. Once a year, participants will provide blood samples for clinical lab analysis and genetic testing. Every two years, participants will provide cerebrospinal fluid samples, undergo positron emission topography (PET) and MRI brain scans, and complete a series of tests to assess cognitive function, risk factors, and other measures.
Minimum Age: 50 Years
Maximum Age: 90 Years
Contact study personnel listed either under the general study contact or the location nearest you.
Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.
Banner Alzheimer's Institute
Phoenix, AZ 85006
Lead: Banner Health
Source: ClinicalTrials.gov ID: NCT04994847