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Find more clinical trials

Magnesium L-Threonate to Enhance Learning and Memory in People with Dementia

Start: July 2014
End: July 2016
Enrollment: 20

What Is This Study About?

This study will examine the effects of taking a dietary supplement, magnesium L-threonate (brand name, Magtein), in people with mild to moderate dementia and a magnesium deficiency to see if it will improve memory and/or magnesium deficiency.

Do I Qualify To Participate in This Study?

Minimum Age: 60 Years

Maximum Age: N/A

Must have:

  • Mini-Mental State Examination score of 16-24
  • Adequate seeing and hearing ability to allow neuropsychological testing
  • More than 12 years of educational achievement or a General Education Development certificate
  • Women must be surgically sterile, postmenopausal, or use an acceptable method of birth control

Must NOT have:

  • Active heart disease
  • Uncontrolled high blood pressure (≥ 140/90 mmHg)
  • Renal or hepatic impairment/disease
  • Type I diabetes
  • Unstable thyroid disease
  • Psychiatric disorder requiring hospitalization in the past year
  • Drug or alcohol abuse in the past 12 months
  • Immune disorder such as HIV/AIDS
  • Transient ischemic attacks, carotid bruits, or verified lacunes
  • Significant pulmonary disease
  • Contraindication for PET scan, including a stroke or heart attack in the past 6 months or inability to lie down for 1 hour
  • History of cancer (except localized skin cancer without metastases or in situ cervical cancer) within 5 years prior to screening
  • Prohibited medications: medications known to interact with magnesium; antibiotics;  vitamins, minerals or dietary/herbal supplements other than the study product until after study completion
  • On an unstable dose of medication (defined as fewer than 90 days at the same dose)
  • Allergy or sensitivity to any ingredient in the test product
  • Pregnant , lactating, or planning to become pregnant during the study period
  • Participation in another research study within 30 days prior to the screening visit

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.


Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: Stanford University

Collaborator Sponsor

  • Magceutics Inc.

Source: ID: NCT02210286

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