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Mediterranean Diet, Weight Loss, and Cognition in Obese Older Adults

Start: September 1, 2016
End: April 1, 2021
Enrollment: 180

What Is This Study About?

Obesity is associated with a higher risk of health problems, including heart disease, hypertension, and diabetes, and may be a risk factor for cognitive decline and dementia. This study will test the effects of a Mediterranean diet and caloric restriction to promote weight loss and improve cognitive function in obese older adults.

Do I Qualify To Participate in This Study?

Minimum Age: 55 Years

Maximum Age: 85 Years

Must have:

  • Body Mass Index of 30-49
  • Minimal levels of cognitive impairment
  • Access to a phone
  • Resident of the Chicago area for the next 14 months
  • Fluent in English

Must NOT have:

  • Montreal Cognitive Assessment score of less than 19 
  • Kidney disease
  • Autoimmune disorder or immunodeficiency
  • Malabsorptive disorder
  • Gastrointestinal or hepatic disease
  • Severe ischemic heart disease, pulmonary disease, or bariatric surgery
  • Alcohol or drug abuse
  • Uncontrolled diabetes
  • Schizophrenia or bipolar disorder
  • Cancer treatment within the past 12 months
  • Weight greater than 450 pounds
  • Diagnosed sleep apnea and regularly using a continuous positive airway pressure therapy machine
  • Currently adhering to a Mediterranean diet
  • Currently on a weight-loss diet or involved in a formal weight-loss program
 
Study Contact
Marian Fitzgibbon, PhD
Lara Blumstein

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Illinois
University Of Illinois at Chicago
Chicago, IL 60608

Who Sponsors This Study?

Lead: University of Illinois at Chicago

Collaborator Sponsor

  • National Institutes of Health (NIH)

Source: ClinicalTrials.gov ID: NCT03129048