Start: September 1, 2016
End: April 1, 2021
What Is This Study About?
Obesity is associated with a higher risk of health problems, including heart disease, hypertension, and diabetes, and may be a risk factor for cognitive decline and dementia. This study will test the effects of a Mediterranean diet and caloric restriction to promote weight loss and improve cognitive function in obese older adults.
Do I Qualify To Participate in This Study?
- Body Mass Index of 30-49
- Minimal levels of cognitive impairment
- Access to a phone
- Resident of the Chicago area for the next 14 months
- Fluent in English
Must NOT have:
- Montreal Cognitive Assessment score of less than 19
- Kidney disease
- Autoimmune disorder or immunodeficiency
- Malabsorptive disorder
- Gastrointestinal or hepatic disease
- Severe ischemic heart disease, pulmonary disease, or bariatric surgery
- Alcohol or drug abuse
- Uncontrolled diabetes
- Schizophrenia or bipolar disorder
- Cancer treatment within the past 12 months
- Weight greater than 450 pounds
- Diagnosed sleep apnea and regularly using a continuous positive airway pressure therapy machine
- Currently adhering to a Mediterranean diet
- Currently on a weight-loss diet or involved in a formal weight-loss program
If I Qualify, Who Do I Contact?
Contact study personnel listed either under the general study contact or the location nearest you.
Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.
Where Is This Study Located?
Lead: University of Illinois at Chicago
National Institutes of Health (NIH)
Source: ClinicalTrials.gov ID: NCT03129048