Mediterranean Diet, Weight Loss, and Cognition in Obese Older Adults

What Is This Study About?

Obesity is associated with a higher risk of health problems, including heart disease, hypertension, and diabetes, and may be a risk factor for cognitive decline and dementia. This study will test the effects of a Mediterranean diet and caloric restriction to promote weight loss and improve cognitive function in obese older adults.

Do I Qualify To Participate in This Study?

Must have:

• Body Mass Index of 30-49
• Minimal levels of cognitive impairment
• Access to a phone
• Resident of the Chicago area for the next 14 months
• Fluent in English

Must NOT have:

• Montreal Cognitive Assessment score of less than 19 
• Kidney disease
• Autoimmune disorder or immunodeficiency
• Malabsorptive disorder
• Gastrointestinal or hepatic disease
• Severe ischemic heart disease, pulmonary disease, or bariatric surgery
• Alcohol or drug abuse
• Uncontrolled diabetes
• Schizophrenia or bipolar disorder
• Cancer treatment within the past 12 months
• Weight greater than 450 pounds
• Diagnosed sleep apnea and regularly using a continuous positive airway pressure therapy machine
• Currently adhering to a Mediterranean diet
• Currently on a weight-loss diet or involved in a formal weight-loss program

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

 

Where Is This Study Located?

Who Sponsors This Study?

Lead: University of Illinois at Chicago

Collaborator Sponsor

• National Institutes of Health (NIH)

Source: ClinicalTrials.gov ID: NCT03129048