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Find more clinical trials

Mindfulness-Based Stress Reduction, Health Education, and Exercise

Start: April 2015
End: May 2021
Enrollment: 580

What Is This Study About?

This study will examine the effects on age-related cognitive decline of mindfulness-based stress reduction (MBSR), aerobic exercise, and their combination, compared with a health discussion group.

Do I Qualify To Participate in This Study?

Minimum Age: 65 Years

Maximum Age: 84 Years

Must have:

  • Living in the community
  • Self-reported cognitive complaints that are a normal part of aging
  • Sedentary

Must NOT have:

  • Known diagnosis of dementia, mild cognitive impairment, or other neurodegenerative illness such as Parkinson's disease or cerebrovascular disease
  • Psychotic disorder or any unstable psychiatric condition
  • Medical conditions that suggest shortened lifespan (such as metastatic cancer), that would prohibit safe participation in the study (including cardiovascular disease or musculoskeletal conditions), or that would interfere with the assessments (such as taking medications for diabetes or ferromagnetic metal/bridgework that would interfere with MRI)
  • IQ of <70
  • Sensory impairment (language, hearing, or visual) that would prevent participation
  • Alcohol abuse within the past 6 months; current illicit drug use
  • Cognitive training, such as brain-training software or other interventions expected to affect neuroplasticity
  • Current meditation practice or prior training
  • Medications that interfere with measurements, including cancer chemotherapy, glucocorticoids, and interferon

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.


Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: Washington University School of Medicine

Collaborator Sponsor

  • University of California, San Diego
  • National Institutes of Health (NIH)
  • National Institute on Aging (NIA)
  • National Center for Complementary and Integrative Health (NCCIH)
  • Office of Behavioral and Social Science Research
  • McKnight Brain Research Foundation

Source: ID: NCT02665481

An official website of the U.S. government, managed by the National Institutes on Aging at the National Institutes of Health