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U.S Department of Health and Human Services (HHS) National Institutes of Health
HomeIn-Home Physical and Mental Exercise Game for Mild Cognitive Impairment (iPACES)
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In-Home Physical and Mental Exercise Game for Mild Cognitive Impairment (iPACES)

Start: August 23, 2021
End: May 31, 2023
Enrollment: 120

What Is This Study About?

This study will test whether an in-home video game that combines physical and mental exercise improves cognition in people with mild cognitive impairment. In the iPACES game, a person pedals an exercise wheel to move along a virtual path. While playing the game, participants will wear a wrist device to track their activity and heart rate. Participants and their study partners from the same household will be randomly assigned together to either the iPACES game or a control group to use a different game. Participants will play their assigned game three to five times a week for at least six months. After six months, participants in the control group will switch over to the iPACES program. At the start of the study and every six months, all participants will provide small blood samples gathered from a finger prick at home. Researchers will evaluate cognitive function and blood test results to measure changes related to exercise and cognition. The exercise game materials, including an exercise wheel and tablet, will be delivered to the participant's home for use during the study. This is a remote study using video conferences and mail. Participants can join from anywhere in the continental United States.

Do I Qualify To Participate in This Study?

Minimum Age: 50 Years

Maximum Age: N/A

Must have:

  • Diagnosis of mild cognitive impairment with a Montreal Cognitive Assessment score of 17 to 25
  • Availability of a study partner from the same household willing to participate in the study
  • Able to exercise three to five times per week for at least six months
  • Able to pedal an exercise wheel
  • Able to read from a small tablet screen
  • Understand English language
  • Adequate vision and hearing to operate tablet touch screen

Must NOT have:

  • Already exercise for 45 minutes or more, five to seven times a week
  • History of heart disease or stroke
  • History of serious memory problems (e.g., Alzheimer's disease)
  • History of other neurological conditions (e.g., seizures, Parkinson's disease)
  • Tremor that could interfere with touch screen use required throughout the study
  • History of motion sickness (e.g., car sickness)

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you. For more information about the study and enroll online, visit the iPACES study website.

 

Who Is the General Study Contact?

This is a remote study using video conferences and mail. Participants can join from anywhere in the continental United States.

Study Contact
Dr. Valerie Needham
Ire Lee - Clinical Research Coordinator

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

New York
iPACES, LLC (Remote study open to participants from anywhere in U.S.)
Clifton Park, NY 12065
Recruiting
Dr. Valerie Needham

Who Sponsors This Study?

Lead: iPACES, LLC

Collaborator Sponsor

  • Pacific Brain Health Center
  • 1st Playable Productions
  • Adirondack Neuropsychological Associates
  • Albany Medical College
  • National Institute on Aging

Source: ClinicalTrials.gov ID: NCT05009524