Start: August 28, 2019
End: October 2027
Transcranial direct current stimulation (tDCS) is a noninvasive therapy that delivers weak electrical current to the brain. This study will investigate the effects of a combination treatment of tDCS and short-term memory therapy in people with the neurodegenerative disease primary progressive aphasia (PPA), which is characterized by the gradual loss of language functioning, and related neurodegenerative conditions. Over the course of a year, participants will undergo training in a series of word sequences along with both stimulation and sham sessions for three-week periods (five sessions in a week, 15 sessions per stimulation site). Researchers will evaluate changes in verbal short-term memory, language abilities, well-being, and quality of life, as well as changes in brain structure and function using MRI.
Minimum Age: 45 Years
Maximum Age: 75 Years
Contact study personnel listed either under the general study contact or the location nearest you.
Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.
Johns Hopkins Hospital
Baltimore, MD 21287
RecruitingKyrana Tsapkini, PhD
Lead: Johns Hopkins University
Source: ClinicalTrials.gov ID: NCT03887481