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Find more clinical trials

Tau PET Imaging and Cognition

Start: June 1, 2018
End: December 2025
Enrollment: 105

What Is This Study About?

Tau is a protein that accumulates abnormally in the brains of people with Alzheimer's disease and other dementias. This study will use the new radioactive tracer 18F-MK-6240 in positron emission tomography (PET) scanning to detect tau pathology in older adults who are cognitively healthy and mildly cognitively impaired. Researchers will examine the interactions between tau levels and performance on cognitive tasks, neural activation patterns using functional MRI brain scans, and other cognitive and behavioral measures. The study also aims to examine how the presence of tau may contribute to the risk of subsequent cognitive decline, neurodegeneration, and dementia.

Do I Qualify To Participate in This Study?

Minimum Age: 55 Years

Maximum Age: 90 Years

Must have:

  • Participation in amyloid PET scanning study
  • Reside near Columbia University Medical Center
  • Willing and able to participate

Must NOT have:

  • Inability to undergo PET, such as metallic implants, pacemaker, claustrophobia, or difficulty lying flat for one hour
  • Pregnant or lactating
  • Current, past, or anticipated exposure to radiation
  • Significant active physical illness

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Study Contact
Reshma Babukutty

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

New York
Columbia University Medical Center
New York, NY 10032
Ashley Mensing, BS

Who Sponsors This Study?

Lead: Yaakov Stern

Collaborator Sponsor

  • National Institute on Aging (NIA)

Source: ID: NCT03372317

An official website of the U.S. government, managed by the National Institutes on Aging at the National Institutes of Health