Training to Reduce Care-Resistant Behaviors in Alzheimer's and TBI (NeuroNS-Care)

What Is This Study About?

This study will test the effectiveness of an Internet-based distance-learning program in reducing care-resistant behaviors, including agitation, aggression, and irritability, in people with Alzheimer's disease or traumatic brain injury (TBI).

Do I Qualify To Participate in This Study?

Must have:

• Possible or probable Alzheimer's disease (of all severity stages) or moderate to severe TBI at least 6 months prior to study enrollment
• Family caregiver (unpaid) who provides support or supervision for at least one instrumental activity of daily living for the affected person, with direct contact averaging 5 of every 7 days, and 21 hours weekly
• Caregiver report of agitation/aggression, disinhibition, or irritability on the Neuropsychiatric Inventory that is triggered by resistance to care-related activities, such as bathing, taking medications, or attending healthcare appointments
• Generally healthy and able to walk (assistance devices such as a walker or cane are allowed)
• Vision and hearing sufficient to complete testing procedures (hearing aid allowed)
• Cognitive function and spoken/written English sufficient to complete neuropsychological testing
• May be on stable doses of psychoactive agents for at least 30 days
• Access to high-speed/broadband Internet service through home computer capable of operating conference software

Must NOT have:

• Evidence of other psychiatric/neurological disorders that could be the primary source of cognitive impairment, such as stroke, Parkinson's disease, schizophrenia, bipolar or unipolar depression, and seizure disorder
• Psychotic features, such as delusions or hallucinations, that are not adequately treated or not on stable medical therapy for at least 30 days
• Alcoholism or drug misuse within past 2 years
• Any condition that would make the participant or caregiver unsuitable for the study

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

 

Where Is This Study Located?

Who Sponsors This Study?

Lead: University of Alabama at Birmingham

Source: ClinicalTrials.gov ID: NCT03734289