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Find more clinical trials

Transcranial Alternating Current Stimulation for Modulation of Sleep and Cognitive Performance

Start: March 7, 2018
End: May 2021
Enrollment: 145

What Is This Study About?

Transcranial alternating current stimulation uses electrodes to deliver small amounts of electricity through the brain and has been shown to enhance slow-wave sleep and improve memory in healthy adults. This study will investigate the effect of stimulation on sleep, thinking and memory, mood, and quality of life in cognitively normal older adults and in individuals with mild cognitive impairment (MCI). Participants will undergo either transcranial alternating current stimulation or sham stimulation during slow-wave sleep and EEG test before and after each night of study session (up to 24 weeks from enrollment for each subject).

Do I Qualify To Participate in This Study?

Minimum Age: 18 Years

Maximum Age: 80 Years

Must have:

  • Diagnosis of amnestic MCI or cognitively normal
  • Native English speaker

Must NOT have:

  • Brain tumors or skull defects
  • Epilepsy
  • Metal implants or devices above the neck
  • Eczema or sensitive skin
  • Insomnia, sleep apnea, narcolepsy, or rapid eye movement-sleep behavior disorder
  • Restless legs syndrome
  • Currently pregnant or trying to become pregnant

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.


Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: University of Colorado, Denver

Source: ID: NCT03112902

An official website of the U.S. government, managed by the National Institute on Aging at the National Institutes of Health