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Transcranial Electrical Stimulation To Improve Memory in Older Adults

Start: October 7, 2021
End: April 30, 2022
Enrollment: 120

What Is This Study About?

This study will evaluate whether a low-risk transcranial electrical stimulation treatment can improve memory in older adults with no cognitive impairment, mild cognitive impairment, or early-stage Alzheimer's disease. Participants will be randomly assigned to receive either the full treatment or a partial, lower dose treatment applied to the right temple and left arm for up to 40 minutes. All participants will undergo an MRI brain scan. One hour after treatment, researchers will test cognitive function, including learning and memory.

Do I Qualify To Participate in This Study?

Minimum Age: 50 Years

Maximum Age: 90 Years

Must have:

  • No cognitive impairment, mild cognitive impairment, or early-stage Alzheimer's disease
  • Right-handed
  • Learned English by 7 years old
  • If unable to provide informed consent, have a legally authorized representative provide consent on their behalf
  • Have available caregiver who can help provide health history information

Must NOT have:

  • Significant history of psychiatric disorders or current psychosis
  • Self-reported depression or Geriatric Depression Scale score of > 5
  • Current excessive use of drugs, alcohol, or nicotine
  • History of epilepsy, migraines, severe stroke, or traumatic brain injury
  • Taking medications with significant psychotropic effects
  • Severe sensory impairment
  • Severe chronic illness in which participation in the study could put a participant at an unusual level of risk
  • Severe cognitive issues
  • Requires a service or support animal
  • Substantial prior experience with neurostimulation treatments that could interfere with study design
  • Metal or electronic implants that could be affected or interfere with neurostimulation
  • Any condition that could make having an MRI unsafe (e.g., metal implants or devices, claustrophobia, epilepsy, or morbid obesity)
  • Sensitivity to any components of the intervention electrodes, such as nickel or latex
  • Any COVID-19 symptoms


If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Study Contact
Research Assistant

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

New Mexico
Mind Research Network
Albuquerque, NM 87106
Vincent P Clark

Who Sponsors This Study?

Lead: The Mind Research Network

Source: ID: NCT05077826