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Transcranial Magnetic Stimulation to Increase Executive Function in Older Adults

Start: August 15, 2016
End: March 16, 2020
Enrollment: 350

What Is This Study About?

In this study researchers are investigating the use of repetitive transcranial magnetic stimulation (TMS) to enhance working memory performance in older adults.

Do I Qualify To Participate in This Study?

Minimum Age: 18 Years

Maximum Age: 80 Years

Must have:

  • Younger group: 18 to 35 years old; older group: 60 to 80 years old
  • Use of effective method of birth control for women of childbearing capacity
  • Willing to provide informed consent

Must NOT have:

  • Substance abuse or dependence in past 6 months
  • Current serious medical illness
  • History of seizure, epilepsy, stroke, brain surgery, head injury, cranial metal implants, known structural brain lesion, or devices that may be affected by repetitive TMS or magnetic resonance imaging (MRI), including pacemaker, medication pump, cochlear implant, or implanted brain stimulator
  • Diagnosed Axis I disorder
  • Dementia Rating Scale-2 score of less than 8
  • Clinically defined neurological disorder
  • Increased risk of seizure for any reason, including prior diagnosis of increased intracranial pressure, or currently taking medication that lowers the seizure threshold
  • Claustrophobia (MRI scanner)
  • Pregnancy

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

 

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: Duke University

Collaborator Sponsor

  • National Institute on Aging (NIA)

Source: ClinicalTrials.gov ID: NCT02767323