Start:
June 2021
End:
December 2025
Enrollment:
120
The Trial-Ready Cohort - Down Syndrome (TRC-DS) study will enroll people with Down syndrome who have no symptoms of dementia to participate in future Alzheimer's disease prevention studies. TRC-DS participants will undergo cognitive and clinical assessments, genetic and biomarker testing, and brain imaging and other tests. Researchers will analyze this information to improve methods for tracking Alzheimer's disease progression. During the study, TRC-DS researchers may refer participants to other studies, including the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) study. Participation in any of these other studies is always optional.
Minimum Age: 25 Years
Maximum Age: 55 Years
Who Is the General Study Contact?
For more information and to enroll, visit the TRC-DS study website.
Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.
Arizona | |
---|---|
Barrow Neurological Institute
Phoenix,
AZ
85013
Recruiting
| |
California | |
University of California, Irvine School of Medicine (co-enrolling through ABC-DS only)
Orange,
CA
92868
Recruiting
| |
Colorado | |
Linda Crnic Institute for Down Syndrome, University of Colorado
Aurora,
CO
80045
Recruiting
| |
Indiana | |
Indiana University
Indianapolis,
IN
46202
Recruiting
| |
Kansas | |
University of Kansas
Kansas City,
KS
66160
Not yet recruiting
| |
Kentucky | |
University of Kentucky (co-enrolling through ABC-DS only)
Lexington,
KY
40504
Recruiting
| |
Massachusetts | |
Massachusetts General Hospital (co-enrolling through ABC-DS only)
Boston,
MA
02114
Recruiting
| |
Missouri | |
Washington University, St. Louis (co-enrolling through ABC-DS only)
Saint Louis,
MO
63108
Recruiting
| |
New York | |
New York State Institute for Basic Research in Developmental Disabilities (SIBRDD) - (Co-enrolling through ABC-DS study only)
Staten Island,
NY
10314
Recruiting
| |
Ohio | |
Case Western Reserve University
Beachwood,
OH
44122
Recruiting
| |
Pennsylvania | |
University of Pittsburgh (co-enrolling through ABC-DS only)
Pittsburgh,
PA
15213
Recruiting
| |
Tennessee | |
Vanderbilt University Medical Center Center for Cognitive Medicine
Nashville,
TN
37212
Recruiting
| |
Wisconsin | |
University of Wisconsin - Madison, Waisman Center (co-enrolling through ABC-DS study only)
Madison,
WI
53705
Recruiting
|
Lead: University of Southern California
Source: ClinicalTrials.gov ID: NCT04165109
An official website of the U.S. government, managed by the National Institute on Aging at the National Institutes of Health