Skip to main content
U.S. flag

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock (  ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Find more clinical trials

Virtual Reality Exercise and Cognitive Training Program to Prevent Alzheimer's in At-Risk Older Adults

Start: October 1, 2019
End: October 2021
Enrollment: 96

What Is This Study About?

This study is designed to combine the effects of physical exercise and cognitive training to improve cognition and reduce the risk of Alzheimer's disease (AD). The Phase 2 randomized controlled trial (RCT) will test the effects of Exergame, a combination of virtual reality cognitive training games and stationary bicycle cycling, on cognition, aerobic fitness, and physical function in persons with subjective cognitive decline at risk for developing AD. Participants will be randomly assigned to one of three study groups and participate three times per week for 12 weeks.

Do I Qualify To Participate in This Study?

Minimum Age: 65 Years

Maximum Age: N/A

Must have:

  • Cognitive complaint (defined as answering yes to the question: "Do you feel that your memory or thinking skills have gotten worse recently within the last 2 years?")
  • Not engaging in aerobic exercise or cognitive training more than two days/week, 30 minutes a session, in the past three months
  • Ability to provide written consent
  • Doctor's approval to participate in a supervised exercise program

Must NOT have:

  • Resting heart rate of greater than 100 or less than 50 beats/min with symptoms
  • Dementia or mild cognitive impairment (self-report, diagnosis, or scoring <26 on the Telephone Interview for Cognitive Status test)
  • Evidence that cognitive decline or memory complaints were caused by underlying neurological or psychiatric disorder or chemical dependency, as determined by doctor
  • Current enrollment in another study
  • Symptoms, medical conditions, or other factors that make exercise impossible or unsafe

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Study Contact
Russell L Spafford, MS
Sue Greimel, MS

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

University of Minnesota
Minneapolis, MN 55455
Russell L Spafford, MS

Who Sponsors This Study?

Lead: Moai Technologies LLC

Collaborator Sponsor

  • University of Minnesota

Source: ID: NCT04311736

An official website of the U.S. government, managed by the National Institutes on Aging at the National Institutes of Health