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La información sobre este estudio está en inglés.

Si necesita ayuda en español, comuníquese con el Centro de Educación y Referencias sobre la Enfermedad de Alzheimer y las Demencias Relacionadas (ADEAR, por sus siglas en inglés) por teléfono al 800-438-4380 o envíe un correo electrónico. También puede llamar o enviar un correo electrónico al contacto del estudio (en inglés) para obtener información adicional.

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Cognitive Function in Adults With and Without HIV

Start: December 2015
End: December 2018
Enrollment: 30

What Is This Study About?

This study will test two different drugs, alone and in combination, to assess their effect on cognitive function in people with HIV as they age. The study will help researchers learn about the contribution of the neuronal cholingeric receptor system to cognitive impairment in this population.

Do I Qualify To Participate in This Study?

Minimum Age: 35 Years

Maximum Age: N/A

Must have:

  • HIV-positive for at least 5 years (on antiretroviral therapy for at least 6 months with a recent viral load, within 6 months, of less than 50 and CD4 count of more than 200) or HIV-negative, at-risk individuals
  • Negative urine pregnancy test
  • Adequate visual and auditory ability to complete neuropsychological testing

Must NOT have:

  • Unmanaged HIV Infection, identified by no current medication regimen or the presence of one or more AIDS-defining conditions
  • Antiretroviral regimen that includes a protease inhibitor medication
  • History of heart disease or abnormal electrocardiograph at screening
  • Heavy use of nicotine
  • Current alcohol or substance abuse
  • Current use of antipsychotics, benzodiazepines, or other psychoactive medications
  • Psychiatric disorder
  • Heart attack in the past year or unstable or severe cardiovascular disease

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.


Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: Vanderbilt University Medical Center

Source: ID: NCT03244488