Down Syndrome Clinical Trials Network-Study of Alzheimer's Disease

What Is This Study About?

Adults with Down syndrome are at increased risk for Alzheimer's disease as they age. The Longitudinal Investigation for the Enhancement of Down Syndrome Research (LIFE-DSR) is an observational study to understand the cognitive and behavioral changes and health issues in adults with Down syndrome as they progress toward Alzheimer's disease. Over two years, the researchers will assess changes in cognition, behavior, function, and health in people with Down syndrome. Blood will also be collected to find biomarkers that could help diagnose and track disease progression.

Do I Qualify To Participate in This Study?

Must have:

• Diagnosis of Down syndrome
• Study partner who has regular interaction, can participate in annual clinic visits, and can respond to questions about the participant
• Participant and study partner must be capable of reliably completing study assessments

Must NOT have:

• Participants and study partners who are not able to complete trial procedures or adhere to the schedule of study assessments

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

 

Who Is the General Study Contact?

For more information about this study or study sites, visit About LIFE-DSR.

Where Is This Study Located?

Arizona
Barrow Neurological Institute Phoenix, AZ 85013 Recruiting Sandy Quintanilla 602-406-7054 sandy.quintanilla@dignityhealth.org
California
University California Irvine Irvine, CA 92697 Recruiting Kelly Kilday 714-456-8443 kkilday@uci.edu
University of California, San Diego La Jolla, CA 92093 Recruiting Emily Little e2little@health.ucsd.edu
Georgia
Emory University Atlanta, GA 30322 Recruiting Helen Smith 404-778-8477 hsmith3@emory.com
Illinois
Rush University Medical Center Chicago, IL 60612 Recruiting Melissa Baer 312-563-6636 melissa_r_baer@rush.edu
Advocate Health Park Ridge, IL 60068 Recruiting Monika Kapinos 847-723-2243 monika.kapinos@advocatehealth.com
Kansas
Kansas University Medical Center Fairway, KS 66205 Recruiting Kayla Meyer 913-588-0073 kmeyer5@kumc.edu
Kentucky
University Of Kentucky Lexington, KY 40536 Recruiting Roberta Davis 859-218-3865 roberta.davis@uky.edu
Maryland
Kennedy Krieger Institute Baltimore, MD 21205 Recruiting Naomi Franklin FranklinN@kennedykrieger.org
Massachusetts
Massachusetts General Hospital Boston, MA 02114 Recruiting Ashlee Campbell 671-726-7954 acampbell18@mgh.harvard.edu
Massachusetts General Hospital Charlestown, MA 02129 Recruiting Kelsey Shelofsky 617-726-5892 kshelofsky@mgh.harvard.edu
North Carolina
Duke University Medical Center Durham, NC 27710 Recruiting Gretchen Nichting 919-660-0757 gretchen.nichting@duke.edu
Ohio
Cincinnatti Children's Hospital Medical Center Cincinnati, OH 45229 Recruiting Kellie Voth 513-636-0674 Kellie.Ramsdale@cchmc.org
Case Western Reserve University Cleveland, OH 044106 Recruiting Melissa Stasko 216-844-7281 melissa.stasko@case.edu

Who Sponsors This Study?

Lead: LuMind IDSC Foundation

Collaborator Sponsor

• Alzheimer's Disease Cooperative Study (ADCS)

Source: ClinicalTrials.gov ID: NCT04149197