Transcranial Magnetic Stimulation To Improve Cognition and Stress Resilience

What Is This Study About?

Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive way to stimulate parts of the brain using a magnet. This study will test whether rTMS can improve attention, memory, and the ability to recover from stressful situations. Participants will receive up to 10, three-minute rTMS treatments every day over five days. In addition, participants will undergo an MRI brain scan at the start of the study and one week after the intervention. The researchers will also measure cognition, stress resilience, and depression before and after the intervention, within one week, and after one month.

Do I Qualify To Participate in This Study?

Must have:

• An associate degree education or higher
• Able to read and understand questionnaires and informed consent

Must NOT have:

• Any current psychiatric diagnosis or current Clinical Global Impression ratings of psychiatric illness > 1
• Current physical illness or ongoing abnormal laboratory test results
• History of neurological disease, concussion, overnight hospitalization, tumors, seizures, meningitis, encephalitis, or abnormal brain scans (e.g., MRI)
• Moderate to severe traumatic brain injury 
• Frequent or severe headaches
• Current or past use of a psychotropic medication, such as drugs to treat anxiety, depression, or psychosis
• Females of childbearing potential who are pregnant, nursing, or are not using a reliable form of birth control
• Current participation or plan to enroll in another clinical trial
• Repeated abuse or dependence upon drugs (excluding nicotine and caffeine)
• Implanted devices or metal of any kind

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

 

Where Is This Study Located?

Who Sponsors This Study?

Lead: Medical University of South Carolina

Collaborator Sponsor

• National Aeronautics and Space Administration (NASA)
• The Translational Research Institute for Space Health (TRISH)

Source: ClinicalTrials.gov ID: NCT04123496