Study finds that Alzheimer’s neurons accumulate more DNA variants than occur from aging alone. The pattern of the variants is linked to oxidative damage and problems with DNA repair processes.
Hydroxychloroquine is linked to lower dementia risk in older individuals and can reduce molecular signs of Alzheimer’s in mouse and cell models, according to an NIA study.
A research team led by NIH’s Center for Alzheimer’s and Related Dementias found 45 associations between viruses and neurodegenerative diseases with the strongest link between viral encephalitis and Alzheimer’s.
Researchers have observed how a molecule found in green tea dismantles tau tangles found in Alzheimer’s disease, leading to discovery of additional molecules that can untangle tau and are potential Alzheimer’s treatments.
Some viral illnesses may increase a person’s chances of later developing Alzheimer’s disease or another neurodegenerative disorder. Though a causal link cannot be confirmed, an NIH study found significant associations.
Education and other disparities may explain gender differences in late-life cognition, according to an NIA-funded study of data from nearly 50,000 older adults in India.